Cargando…

Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells

Signal transducer and activator of transcription 3 (STAT3) and telomerase are considered attractive targets for anticancer therapy. The in vitro anticancer activity of the gold(I) compound auranofin was investigated using MDA-MB 231 human breast cancer cells, in which STAT3 is constitutively active....

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Nam-Hoon, Park, Hyo Jung, Oh, Mi-Kyung, Kim, In-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133824/
https://www.ncbi.nlm.nih.gov/pubmed/23351386
http://dx.doi.org/10.5483/BMBRep.2013.46.1.123