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Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells
Signal transducer and activator of transcription 3 (STAT3) and telomerase are considered attractive targets for anticancer therapy. The in vitro anticancer activity of the gold(I) compound auranofin was investigated using MDA-MB 231 human breast cancer cells, in which STAT3 is constitutively active....
Autores principales: | Kim, Nam-Hoon, Park, Hyo Jung, Oh, Mi-Kyung, Kim, In-Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133824/ https://www.ncbi.nlm.nih.gov/pubmed/23351386 http://dx.doi.org/10.5483/BMBRep.2013.46.1.123 |
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