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Somatic mutation patterns and compound response in cancers

The use of various cancer cell lines can recapitulate known tumor-associated mutations and genetically define cancer subsets. This approach also enables comparative surveys of associations between cancer mutations and drug responses. Here, we analyzed the effects of ∼40,000 compounds on cancer cell...

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Detalles Bibliográficos
Autores principales: He, Ningning, Kim, Nayoung, Yoon, Sukjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133857/
https://www.ncbi.nlm.nih.gov/pubmed/23433112
http://dx.doi.org/10.5483/BMBRep.2013.46.2.226