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Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer

Aging is the strongest risk factor for cancer development, suggesting that molecular crosstalks between aging and tumorigenesis exist in many cellular pathways. Recently, Sirtuins (Sirt1-7), the mammalian homologues of aging-related sir2α in yeast, have been shown to modulate several major cellular...

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Detalles Bibliográficos
Autores principales: Cha, Yong I., Kim, Hyun-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133878/
https://www.ncbi.nlm.nih.gov/pubmed/24064057
http://dx.doi.org/10.5483/BMBRep.2013.46.9.180