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Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor

The ATP-binding cassette transporters ABCG5 and ABCG8 form heterodimers that limit absorption of dietary sterols in the intestine and promote cholesterol elimination from the body through hepatobiliary secretion. To identify cis-regulatory elements of the two genes, we have cloned and analyzed twent...

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Detalles Bibliográficos
Autores principales: Back, Su Sun, Kim, Jinsu, Choi, Daehyung, Lee, Eui Sup, Choi, Soo Young, Han, Kyuhyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133900/
https://www.ncbi.nlm.nih.gov/pubmed/23790976
http://dx.doi.org/10.5483/BMBRep.2013.46.6.246