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Endothelin-1 enhances the melanogenesis via MITF-GPNMB pathway

Endothelin-1 (ET-1) plays an indispensable role in epidermal pigmentation in hyperpigmentary disorders due to a central role in melanogenesis. Nevertheless, precise mechanism involved in ET-1-induced hyperpigmentation is still undefined. Glycoprotein (transmembrane) non-metastatic melanoma protein b...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Liu, Wei, Yuan, Xiaoying, Li, Dongguang, Gu, Weijie, Gao, Tianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133913/
https://www.ncbi.nlm.nih.gov/pubmed/23884103
http://dx.doi.org/10.5483/BMBRep.2013.46.7.250