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Target-directed development and preclinical characterization of the proposed biosimilar rituximab GP2013
Biosimilar development involves a target-directed iterative process to ensure a similar product to the originator. Here we report the preclinical development of the proposed biosimilar rituximab (GP2013). Post-translational modifications and bioactivities of GP2013 versus originator rituximab were e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133973/ https://www.ncbi.nlm.nih.gov/pubmed/24024472 http://dx.doi.org/10.3109/10428194.2013.843090 |