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Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssi

Replication slippage or slipped-strand mispairing involves the misalignment of DNA strands during the replication of repeated DNA sequences, and can lead to genetic rearrangements such as microsatellite instability. Here, we show that PolB and PolD replicative DNA polymerases from the archaeal model...

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Detalles Bibliográficos
Autores principales: Castillo-Lizardo, Melissa, Henneke, Ghislaine, Viguera, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134008/
https://www.ncbi.nlm.nih.gov/pubmed/25177316
http://dx.doi.org/10.3389/fmicb.2014.00403