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Efficacy of the small molecule inhibitor of Lipid II BAS00127538 against Acinetobacter baumannii

OBJECTIVE: To test the activity of a small molecule compound that targets Lipid II against Acinetobacter baumannii. METHODS: Susceptibility to small molecule Lipid II inhibitor BAS00127538 was assessed using carbapenem- and colistin-resistant clinical isolates of A. baumannii. In addition, synergy b...

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Detalles Bibliográficos
Autor principal: de Leeuw, Erik PH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134019/
https://www.ncbi.nlm.nih.gov/pubmed/25143710
http://dx.doi.org/10.2147/DDDT.S68020