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Supercritical fluid-mediated liposomes containing cyclosporin A for the treatment of dry eye syndrome in a rabbit model: comparative study with the conventional cyclosporin A emulsion

BACKGROUND: The objective of this study was to compare the efficacy of cyclosporin (CsA)-encapsulated liposomes with the commercially available CsA emulsion (Restasis(®)) for the treatment of dry eye syndrome in rabbits. METHODS: Liposomes containing CsA were prepared by the supercritical fluid (SCF...

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Detalles Bibliográficos
Autores principales: Karn, Pankaj Ranjan, Kim, Hyun Do, Kang, Han, Sun, Bo Kyung, Jin, Su-Eon, Hwang, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134020/
https://www.ncbi.nlm.nih.gov/pubmed/25143728
http://dx.doi.org/10.2147/IJN.S65601