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Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor

BACKGROUND: Cytokine-induced killer (CIK) cells are an emerging approach of cancer treatment. Our previous study have shown that CIK cells stimulated with combination of IL-2 and IL-15 displayed improved proliferation capacity and tumor cytotoxicity. However, the mechanisms of CIK cell proliferation...

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Detalles Bibliográficos
Autores principales: Wang, Wenju, Meng, Mingyao, Zhang, Yayong, Wei, Chuanyu, Xie, Yanhua, Jiang, Lihong, Wang, Chunhui, Yang, Fang, Tang, Weiwei, Jin, Xingfang, Chen, Dai, Zong, Jie, Hou, Zongliu, Li, Ruhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134122/
https://www.ncbi.nlm.nih.gov/pubmed/25108500
http://dx.doi.org/10.1186/1755-8794-7-49