Cargando…

Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor

BACKGROUND: Cytokine-induced killer (CIK) cells are an emerging approach of cancer treatment. Our previous study have shown that CIK cells stimulated with combination of IL-2 and IL-15 displayed improved proliferation capacity and tumor cytotoxicity. However, the mechanisms of CIK cell proliferation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Wenju, Meng, Mingyao, Zhang, Yayong, Wei, Chuanyu, Xie, Yanhua, Jiang, Lihong, Wang, Chunhui, Yang, Fang, Tang, Weiwei, Jin, Xingfang, Chen, Dai, Zong, Jie, Hou, Zongliu, Li, Ruhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134122/ https://www.ncbi.nlm.nih.gov/pubmed/25108500 http://dx.doi.org/10.1186/1755-8794-7-49

Ejemplares similares

MicroRNA profiling of CD3(+)CD56(+) cytokine-induced killer cells
por: Wang, Wenju, et al.
Publicado: (2015)

Association between 5, 10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms and congenital heart disease: A meta-analysis()
por: Wang, Wenju, et al.
Publicado: (2013)

Analysis of NKX2-5 in 439 Chinese Patients with Sporadic Atrial Septal Defect
por: Wang, Hongshu, et al.
Publicado: (2019)

Impact of cytotoxic T lymphocytes immunotherapy on prognosis of colorectal cancer patients
por: Zhu, Yankun, et al.
Publicado: (2023)

CD300LG improves the cytotoxic activity of CIK
por: Wang, Qiuyue, et al.
Publicado: (2017)

All-trans retinoic acid enhances cytotoxicity of CIK cells against human lung adenocarcinoma by upregulating MICA and IL-2 secretion
por: Fan, Xiao-yan, et al.
Publicado: (2017)

Improving Clinical Manufacturing of IL-15 Activated Cytokine-Induced Killer (CIK) Cells
por: Bremm, Melanie, et al.
Publicado: (2019)

Retrospective analysis of the efficacy of adjuvant cytokine‐induced killer cell immunotherapy combined with chemotherapy in colorectal cancer patients after surgery
por: Li, Xiao, et al.
Publicado: (2022)

The prognostic significance of fibroblast activation protein-α in human lung adenocarcinoma
por: Shi, Jianlin, et al.
Publicado: (2020)

OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis
por: Lin, Zhuying, et al.
Publicado: (2021)

A dynamic transcriptomic atlas of cytokine-induced killer cells
por: Meng, Mingyao, et al.
Publicado: (2018)

Impact of FAK Expression on the Cytotoxic Effects of CIK Therapy in Triple-Negative Breast Cancer
por: Pan, Mei-Ren, et al.
Publicado: (2019)

IL-1 and IL-4 as reciprocal regulators of IL-2 induced lymphocyte cytotoxicity.
por: Ebina, N., et al.
Publicado: (1990)

CIK Cells and HDAC Inhibitors in Multiple Myeloma
por: Stephan, David, et al.
Publicado: (2017)

Cik1 and Vik1 accessory proteins confer distinct functions to the kinesin-14 Kar3
por: Bergman, Zane J., et al.
Publicado: (2023)

Innovative Clinical Perspectives for CIK Cells in Cancer Patients
por: Introna, Martino, et al.
Publicado: (2018)

Diagnostic Value of Serum Levels of IL-22, IL-23, and IL-17 for Idiopathic Pulmonary Fibrosis Associated with Lung Cancer
por: Zhang, Qian, et al.
Publicado: (2022)

IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections
por: Slaats, Jeroen, et al.
Publicado: (2016)

Novel Genetic Variants of Sporadic Atrial Septal Defect (ASD) in a Chinese Population Identified by Whole-Exome Sequencing (WES)
por: Liu, Yong, et al.
Publicado: (2018)

Associations of IL-4, IL-4R, and IL-13 Gene Polymorphisms in Coal Workers' Pneumoconiosis in China: A Case-Control Study
por: Wang, Meilin, et al.
Publicado: (2011)

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
por: Tapia, Victor S., et al.
Publicado: (2019)

Distinct modes of action of CD40L and adaptive cytokines IL-2, IL-4/13, IL-10 and IL-21 on rainbow trout IgM(+) B cells
por: Abos, Beatriz, et al.
Publicado: (2020)

Comparative Proteomic Analysis of Lysine Acetylation in Fish CIK Cells Infected with Aquareovirus
por: Guo, Hong, et al.
Publicado: (2017)

IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions
por: Floss, Doreen M., et al.
Publicado: (2020)

Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation
por: Sasaki, Yuki, et al.
Publicado: (2020)

The diagnostic utility of IL-10, IL-17, and PCT in patients with sepsis infection
por: Zhang, Wei, et al.
Publicado: (2022)

Enhanced Expression of IL-18 and IL-18BP in Plasma of Patients with Eczema: Altered Expression of IL-18BP and IL-18 Receptor on Mast Cells
por: Hu, Yalin, et al.
Publicado: (2017)

SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8(+) T cells
por: Loyal, Lucie, et al.
Publicado: (2020)

The combination of dendritic cells-cytotoxic T lymphocytes/cytokine-induced killer (DC-CTL/CIK) therapy exerts immune and clinical responses in patients with malignant tumors
por: Wang, Ying, et al.
Publicado: (2015)

Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety
por: Ma, Yue, et al.
Publicado: (2012)

CIK细胞及其在肺癌治疗中的研究进展
Publicado: (2011)

Autologous CIK Cell Immunotherapy in Patients with Renal Cell Carcinoma after Radical Nephrectomy
por: Zhang, Yajing, et al.
Publicado: (2013)

Effect of interleukins (IL-2, IL-15, IL-18) on receptors activation and cytotoxic activity of natural killer cells in breast cancer cell
por: Widowati, Wahyu, et al.
Publicado: (2020)

Prognostic value of serum IL-8 and IL-10 in patients with ovarian cancer undergoing chemotherapy
por: Zhang, Lixia, et al.
Publicado: (2019)

A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic Cancer Cells
por: Garofano, Francesca, et al.
Publicado: (2022)

Acute exercise mobilizes NKT-like cells with a cytotoxic transcriptomic profile but does not augment the potency of cytokine-induced killer (CIK) cells
por: Zúñiga, Tiffany M., et al.
Publicado: (2022)

Differential Capacity of Human Skin Dendritic Cells to Polarize CD4(+)T Cells into IL-17, IL-21 and IL-22 Producing Cells
por: Penel-Sotirakis, Karine, et al.
Publicado: (2012)

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression
por: Malireddi, R.K. Subbarao, et al.
Publicado: (2022)

Compared to the amniotic membrane, Wharton’s jelly may be a more suitable source of mesenchymal stem cells for cardiovascular tissue engineering and clinical regeneration
por: Pu, Lei, et al.
Publicado: (2017)

Effect of CIK on multidrug-resistance reversal and increasing the sensitivity of ADR in K562/ADR cells
por: WANG, LEI, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_77055c3le47n4psbbcnpjn7rnv