EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage

BACKGROUND: We have previously demonstrated the epidermal growth factor receptor (EGFR)-targeted hybrid plasmonic magnetic nanoparticles (225-NP) produce a therapeutic effect in human lung cancer cell lines in vitro. In the present study, we investigated the molecular mechanism of 225-NP-mediated an...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuroda, Shinji, Tam, Justina, Roth, Jack A, Sokolov, Konstantin, Ramesh, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134185/
https://www.ncbi.nlm.nih.gov/pubmed/25143731
http://dx.doi.org/10.2147/IJN.S65990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134185/
https://www.ncbi.nlm.nih.gov/pubmed/25143731
http://dx.doi.org/10.2147/IJN.S65990

Ejemplares similares