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EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage

BACKGROUND: We have previously demonstrated the epidermal growth factor receptor (EGFR)-targeted hybrid plasmonic magnetic nanoparticles (225-NP) produce a therapeutic effect in human lung cancer cell lines in vitro. In the present study, we investigated the molecular mechanism of 225-NP-mediated an...

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Detalles Bibliográficos
Autores principales:	Kuroda, Shinji, Tam, Justina, Roth, Jack A, Sokolov, Konstantin, Ramesh, Rajagopal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134185/ https://www.ncbi.nlm.nih.gov/pubmed/25143731 http://dx.doi.org/10.2147/IJN.S65990

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