Cargando…
Nerve Growth Factor Mediates a Switch in Intracellular Signaling for PGE(2)-Induced Sensitization of Sensory Neurons from Protein Kinase A to Epac
We examined whether nerve growth factor (NGF), an inflammatory mediator that contributes to chronic hypersensitivity, alters the intracellular signaling that mediates the sensitizing actions of PGE(2) from activation of protein kinase A (PKA) to exchange proteins directly activated by cAMP (Epacs)....
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134201/ https://www.ncbi.nlm.nih.gov/pubmed/25126967 http://dx.doi.org/10.1371/journal.pone.0104529 |