Cargando…

Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis

High mobility group box chromosomal protein 1 (HMGB-1) released from injured cells plays an important role in the development of arthritis. This study investigated the anti-angiogenic effects of cilostazol in collagen-induced arthritis (CIA) of mice, and the underlying mechanisms involved. The expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hye Young, Park, So Youn, Lee, Sung Won, Lee, Hye Rin, Lee, Won Suk, Rhim, Byung Yong, Hong, Ki Whan, Kim, Chi Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134224/
https://www.ncbi.nlm.nih.gov/pubmed/25126750
http://dx.doi.org/10.1371/journal.pone.0104743