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Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis
High mobility group box chromosomal protein 1 (HMGB-1) released from injured cells plays an important role in the development of arthritis. This study investigated the anti-angiogenic effects of cilostazol in collagen-induced arthritis (CIA) of mice, and the underlying mechanisms involved. The expre...
Autores principales: | Kim, Hye Young, Park, So Youn, Lee, Sung Won, Lee, Hye Rin, Lee, Won Suk, Rhim, Byung Yong, Hong, Ki Whan, Kim, Chi Dae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134224/ https://www.ncbi.nlm.nih.gov/pubmed/25126750 http://dx.doi.org/10.1371/journal.pone.0104743 |
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