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Thermodynamics of the Interaction between Alzheimer's Disease Related Tau Protein and DNA

Tau hyperphosphorylation can be considered as one of the hallmarks of Alzheimer's disease and other tauophaties. Besides its well-known role as a microtubule associated protein, Tau displays a key function as a protector of genomic integrity in stress situations. Phosphorylation has been proven...

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Detalles Bibliográficos
Autores principales: Camero, Sergio, Benítez, María J., Cuadros, Raquel, Hernández, Félix, Ávila, Jesús, Jiménez, Juan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134230/
https://www.ncbi.nlm.nih.gov/pubmed/25126942
http://dx.doi.org/10.1371/journal.pone.0104690