Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation with Small Arginine-Rich Cell-Penetrating Peptide (R/W)9

Peptide nucleic acids (PNAs) are very attractive antisense and antigene agents, but these molecules are not passively taken into cells. Here, using a functional cell assay and fluorescent-based methods, we investigated cell uptake and antisense activity of a tridecamer PNA that targets the HIV-1 pol...

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Detalles Bibliográficos
Autores principales: Cordier, Céline, Boutimah, Fatima, Bourdeloux, Mathilde, Dupuy, Florian, Met, Elisabeth, Alberti, Patrizia, Loll, François, Chassaing, Gérard, Burlina, Fabienne, Saison-Behmoaras, Tula Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134252/
https://www.ncbi.nlm.nih.gov/pubmed/25127364
http://dx.doi.org/10.1371/journal.pone.0104999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134252/
https://www.ncbi.nlm.nih.gov/pubmed/25127364
http://dx.doi.org/10.1371/journal.pone.0104999

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