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Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation with Small Arginine-Rich Cell-Penetrating Peptide (R/W)9
Peptide nucleic acids (PNAs) are very attractive antisense and antigene agents, but these molecules are not passively taken into cells. Here, using a functional cell assay and fluorescent-based methods, we investigated cell uptake and antisense activity of a tridecamer PNA that targets the HIV-1 pol...
Autores principales: | Cordier, Céline, Boutimah, Fatima, Bourdeloux, Mathilde, Dupuy, Florian, Met, Elisabeth, Alberti, Patrizia, Loll, François, Chassaing, Gérard, Burlina, Fabienne, Saison-Behmoaras, Tula Ester |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134252/ https://www.ncbi.nlm.nih.gov/pubmed/25127364 http://dx.doi.org/10.1371/journal.pone.0104999 |
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