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Glioma-Derived ADAM10 Induces Regulatory B Cells to Suppress CD8(+) T Cells

CD8(+) T cells play an important role in the anti-tumor activities of the body. The dysfunction of CD8(+) T cells in glioma is unclear. This study aims to elucidate the glioma cell-derived ADAM10 (A Disintegrin and metalloproteinase domain-containing protein 10) in the suppression of CD8(+) effector...

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Detalles Bibliográficos
Autores principales: Ye, Zhuo-peng, He, Hai-yong, Wang, Hui, Li, Wen-sheng, Luo, Lun, Huang, Zhen-chao, Guo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134303/
https://www.ncbi.nlm.nih.gov/pubmed/25127032
http://dx.doi.org/10.1371/journal.pone.0105350