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Inhibition of Glycogen Synthase Kinase-3β Attenuates Glucocorticoid-Induced Suppression of Myogenic Differentiation In Vitro

Glucocorticoids are the only therapy that has been demonstrated to alter the progress of Duchenne muscular dystrophy (DMD), the most common muscular dystrophy in children. However, glucocorticoids disturb skeletal muscle metabolism and hamper myogenesis and muscle regeneration. The mechanisms involv...

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Detalles Bibliográficos
Autores principales: Ma, Zhenyu, Zhong, Zhigang, Zheng, Zhenyang, Shi, Xing-Ming, Zhang, Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134315/
https://www.ncbi.nlm.nih.gov/pubmed/25127359
http://dx.doi.org/10.1371/journal.pone.0105528