DENR•MCT-1 Promotes Translation Reinitiation Downstream of uORFs to Control Tissue Growth

During cap-dependent eukaryotic translation initiation, ribosomes scan mRNA from the 5′ end to the first AUG start codon with favorable sequence context(1,2). For many mRNAs this AUG belongs to a short upstream open reading frame (uORF)(3), and translation of the main downstream ORF requires reiniti...

Descripción completa

Detalles Bibliográficos
Autores principales: Schleich, Sibylle, Strassburger, Katrin, Janiesch, Philipp Christoph, Koledachkina, Tatyana, Miller, Katharine K., Haneke, Katharina, Cheng, Yong-Sheng, Kuechler, Katrin, Stoecklin, Georg, Duncan, Kent E., Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134322/
https://www.ncbi.nlm.nih.gov/pubmed/25043021
http://dx.doi.org/10.1038/nature13401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134322/
https://www.ncbi.nlm.nih.gov/pubmed/25043021
http://dx.doi.org/10.1038/nature13401

Ejemplares similares