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Lung cell-specific modulation of LPS-induced TLR4 receptor and adaptor localization

Lung infection by Gram-negative bacteria is a major cause of morbidity and mortality in humans. Lipopolysaccharide (LPS), located in the outer membrane of the Gram-negative bacterial cell wall, is a highly potent stimulus of immune and structural cells via the TLR4/MD2 complex whose function is sequ...

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Detalles Bibliográficos
Autores principales: Sender, Vicky, Stamme, Cordula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134348/
https://www.ncbi.nlm.nih.gov/pubmed/25136402
http://dx.doi.org/10.4161/cib.29053