Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA

ISWI-family remodelling enzymes regulate access to genomic DNA by mobilizing nucleosomes(1). These ATP-dependent chromatin remodellers promote heterochromatin formation and transcriptional silencing(1) by generating regularly-spaced nucleosome arrays(2-5). The nucleosome-spacing activity arises from...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, William L., Deindl, Sebastian, Harada, Bryan T., Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134374/
https://www.ncbi.nlm.nih.gov/pubmed/25043036
http://dx.doi.org/10.1038/nature13380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134374/
https://www.ncbi.nlm.nih.gov/pubmed/25043036
http://dx.doi.org/10.1038/nature13380

Ejemplares similares