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Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA

ISWI-family remodelling enzymes regulate access to genomic DNA by mobilizing nucleosomes(1). These ATP-dependent chromatin remodellers promote heterochromatin formation and transcriptional silencing(1) by generating regularly-spaced nucleosome arrays(2-5). The nucleosome-spacing activity arises from...

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Detalles Bibliográficos
Autores principales:	Hwang, William L., Deindl, Sebastian, Harada, Bryan T., Zhuang, Xiaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134374/ https://www.ncbi.nlm.nih.gov/pubmed/25043036 http://dx.doi.org/10.1038/nature13380

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