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Improved Statistical Signal Detection in Pharmacovigilance by Combining Multiple Strength-of-Evidence Aspects in vigiRank: Retrospective Evaluation against Emerging Safety Signals

BACKGROUND: Detection of unknown risks with marketed medicines is key to securing the optimal care of individual patients and to reducing the societal burden from adverse drug reactions. Large collections of individual case reports remain the primary source of information and require effective analy...

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Detalles Bibliográficos
Autores principales: Caster, Ola, Juhlin, Kristina, Watson, Sarah, Norén, G. Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134478/
https://www.ncbi.nlm.nih.gov/pubmed/25052742
http://dx.doi.org/10.1007/s40264-014-0204-5