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Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment response

BACKGROUND: Resistance to chemotherapeutic agents is a major obstacle to cancer treatment. A group of ABC efflux pumps, the Multidrug Resistance Proteins, is a source of resistance. Herein, we investigated the role of ABCC10 in mammary tumours, given the important role we have defined for ABCC10 in...

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Detalles Bibliográficos
Autores principales: Domanitskaya, N, Wangari-Talbot, J, Jacobs, J, Peiffer, E, Mahdaviyeh, Y, Paulose, C, Malofeeva, E, Foster, K, Cai, K Q, Zhou, Y, Egleston, B, Hopper-Borge, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134493/
https://www.ncbi.nlm.nih.gov/pubmed/24937672
http://dx.doi.org/10.1038/bjc.2014.326