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IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling

BACKGROUND: Interleukin-22 (IL-22) has been recently highlighted owing to its biological significance in the modulation of tissue responses during inflammation. However, the role of IL-22 in carcinogenesis has remained unclear. Here, we investigated the pathophysiological significance of IL-22 expre...

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Detalles Bibliográficos
Autores principales: Fukui, H, Zhang, X, Sun, C, Hara, K, Kikuchi, S, Yamasaki, T, Kondo, T, Tomita, T, Oshima, T, Watari, J, Imura, J, Fujimori, T, Sasako, M, Miwa, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134496/
https://www.ncbi.nlm.nih.gov/pubmed/24937671
http://dx.doi.org/10.1038/bjc.2014.336