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Long non-coding RNA MALAT1 promotes tumour growth and metastasis in colorectal cancer through binding to SFPQ and releasing oncogene PTBP2 from SFPQ/PTBP2 complex

BACKGROUND: Metastasis associated with lung adenocarcinoma transcript-1 (MALAT1) is a functional long non-coding RNA (lncRNA), which is highly expressed in several tumours, including colorectal cancer (CRC). Its biological function and mechanism in the prognosis of human CRC is still largely under i...

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Detalles Bibliográficos
Autores principales: Ji, Q, Zhang, L, Liu, X, Zhou, L, Wang, W, Han, Z, Sui, H, Tang, Y, Wang, Y, Liu, N, Ren, J, Hou, F, Li, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134507/
https://www.ncbi.nlm.nih.gov/pubmed/25025966
http://dx.doi.org/10.1038/bjc.2014.383