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Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

[Image: see text] Heat shock protein 70 (Hsp70) is a family of proteins with key roles in regulating malignancy. Cancer cells rely on Hsp70 to inhibit apoptosis, regulate senescence and autophagy, and maintain the stability of numerous onco-proteins. Despite these important biological functions in c...

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Detalles Bibliográficos
Autores principales: Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D., Koren, John, Yan, Pengrong, DaGama Gomes, Erica M., Yang, Chenghua, Patel, Maulik R., Shrestha, Liza, Ochiana, Stefan O., Santarossa, Cristina, Maharaj, Ronnie, Gozman, Alexander, Cox, Marc B., Erdjument-Bromage, Hediye, Hendrickson, Ronald C., Cerchietti, Leandro, Melnick, Ari, Guzman, Monica L., Chiosis, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134716/
https://www.ncbi.nlm.nih.gov/pubmed/24934503
http://dx.doi.org/10.1021/cb500256u