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Identification of novel functional regions within the spike glycoprotein of MHV-A59 based on a bioinformatics approach

Mouse Hepatitis Virus (MHV) is a single-stranded positive sense RNA virus with the ability to promote acute and chronic diseases in mice. The MHV spike protein (S) is a major virulence determinant which in addition to binding to cellular receptors to mediate cell entry and facilitate virus spread to...

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Detalles Bibliográficos
Autores principales: Kaufman, Gili, Liu, Pinghua, Leibowitz, Julian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. Published by Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134989/
https://www.ncbi.nlm.nih.gov/pubmed/24910120
http://dx.doi.org/10.1016/j.virusres.2014.05.023