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Identification of novel functional regions within the spike glycoprotein of MHV-A59 based on a bioinformatics approach
Mouse Hepatitis Virus (MHV) is a single-stranded positive sense RNA virus with the ability to promote acute and chronic diseases in mice. The MHV spike protein (S) is a major virulence determinant which in addition to binding to cellular receptors to mediate cell entry and facilitate virus spread to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V. Published by Elsevier B.V.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134989/ https://www.ncbi.nlm.nih.gov/pubmed/24910120 http://dx.doi.org/10.1016/j.virusres.2014.05.023 |