Alternative lengthening of telomeres (ALT) in cancer stem cells in vivo

Chromosome ends are protected by telomeres which prevent DNA damage response and degradation. Telomerase expression extends telomeres and inhibits DNA damage response. Telomeres are also maintained by the recombination based alternative lengthening pathway. Telomerase is believed to be the sole mech...

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Detalles Bibliográficos
Autores principales: Bojovic, Bojana, Booth, Ryan E., Jin, Yi, Zhou, Xiaofeng, Crowe, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135038/
https://www.ncbi.nlm.nih.gov/pubmed/24531712
http://dx.doi.org/10.1038/onc.2013.603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135038/
https://www.ncbi.nlm.nih.gov/pubmed/24531712
http://dx.doi.org/10.1038/onc.2013.603

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