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Structural proteins of West Nile virus are a major determinant of infectious particle production and fitness in astrocytes

The molecular basis for the increased resistance of astrocytes to a non-neuropathogenic strain of West Nile virus (WNV), WNV-MAD78, compared with the neuropathogenic strain WNV-NY remains unclear. Here, we demonstrated that the reduced susceptibility of astrocytes to WNV-MAD78 is due to a combinatio...

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Detalles Bibliográficos
Autores principales: Hussmann, Katherine L., Vandergaast, Rianna, Zheng, Kang, Hoover, Lisa I., Fredericksen, Brenda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135089/
https://www.ncbi.nlm.nih.gov/pubmed/24920724
http://dx.doi.org/10.1099/vir.0.065474-0