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Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues

Ubiquitylation is a covalent post-translational modification that regulates protein stability and is involved in many biological functions. Proteins may be modified with mono-ubiquitin or ubiquitin chains. Viruses have evolved multiple mechanisms to perturb the cell ubiquitin system and manipulate i...

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Detalles Bibliográficos
Autores principales: Maluquer de Motes, Carlos, Schiffner, Torben, Sumner, Rebecca P., Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135091/
https://www.ncbi.nlm.nih.gov/pubmed/24914067
http://dx.doi.org/10.1099/vir.0.065664-0