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Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive loss of memory and cognitive dysfunctions. A central pathological event of AD is accumulation and deposition of cytotoxic amyloid-β peptide (Aβ) in the brain parenchyma. Heparan sulfate proteoglycans (HSP...

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Detalles Bibliográficos
Autores principales: Zhang, Gan-lin, Zhang, Xiao, Wang, Xiao-min, Li, Jin-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135094/
https://www.ncbi.nlm.nih.gov/pubmed/25157361
http://dx.doi.org/10.1155/2014/516028