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Pinocembrin Protects Human Brain Microvascular Endothelial Cells against Fibrillar Amyloid-β (1−40)Injury by Suppressing the MAPK/NF-κB Inflammatory Pathways

Cerebrovascular accumulation of amyloid-β (Aβ) peptides in Alzheimer's disease (AD) may contribute to disease progression through Aβ-induced microvascular endothelial pathogenesis. Pinocembrin has been shown to have therapeutic effects in AD models. These effects correlate with preservation of...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Li, Jin-ze, Song, Jun-ke, Sun, Jia-lin, Li, Yong-jie, Zhou, Si-bai, Zhang, Tian-tai, Du, Guan-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135138/
https://www.ncbi.nlm.nih.gov/pubmed/25157358
http://dx.doi.org/10.1155/2014/470393