A molecular model of human Lysyl Oxidase (LOX) with optimal copper orientation in the catalytic cavity for induced fit docking studies with potential modulators

Lysyl oxidase (LOX) is a copper dependent amine oxidase which catalyses the cross linking of collagen and elastin towards the maturation of extracellular matrix. The expression and activity of LOX is known to vary under pathological conditions such as tumorigenesis, hyperhomocysteinemia, copper defi...

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Detalles Bibliográficos
Autores principales: Bhuvanasundar, Renganathan, John, Arun, Sulochana, Konerirajapuram Natarajan, Coral, Karunakaran, Deepa, Perinkulam Ravi, Umashankar, Vetrivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135287/
https://www.ncbi.nlm.nih.gov/pubmed/25187679
http://dx.doi.org/10.6026/97320630010406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135287/
https://www.ncbi.nlm.nih.gov/pubmed/25187679
http://dx.doi.org/10.6026/97320630010406

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