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DOCK8 regulates protective immunity by controlling the function and survival of RORγt(+) ILCs

Retinoic-acid receptor-related orphan receptor-γt-positive (RORγt(+)) innate lymphoid cells (ILCs) produce interleukin (IL)-22 and IL-17, which are critical for protective immunity against enteric pathogens. The molecular mechanism underlying the development and survival of RORγt(+) ILCs is not thor...

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Detalles Bibliográficos
Autores principales: Singh, Akhilesh K., Eken, Ahmet, Fry, Mallory, Bettelli, Estelle, Oukka, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135384/
https://www.ncbi.nlm.nih.gov/pubmed/25091235
http://dx.doi.org/10.1038/ncomms5603