Constrained Bithiazoles: Small Molecule Correctors of Defective ΔF508–CFTR Protein Trafficking

[Image: see text] Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. In this study, two sets o...

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Detalles Bibliográficos
Autores principales: Coffman, Keith C., Nguyen, Huy H., Phuan, Puay-Wah, Hudson, Brandi M., Yu, Gui J., Bagdasarian, Alex L., Montgomery, Deanna, Lodewyk, Michael W., Yang, Baoxue, Yoo, Choong L., Verkman, A. S., Tantillo, Dean J., Kurth, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136667/
https://www.ncbi.nlm.nih.gov/pubmed/25061695
http://dx.doi.org/10.1021/jm5007885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136667/
https://www.ncbi.nlm.nih.gov/pubmed/25061695
http://dx.doi.org/10.1021/jm5007885

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