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Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO

[Image: see text] The final step in lanthipeptide biosynthesis involves the proteolytic removal of an N-terminal leader peptide. In the class I lanthipeptide epilancin 15X, this step is performed by the subtilisin-like serine peptidase ElxP. Bioinformatic, kinetic, and mass spectrometric analysis re...

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Detalles Bibliográficos
Autores principales: Ortega, Manuel A., Velásquez, Juan E., Garg, Neha, Zhang, Qi, Joyce, Rachel E., Nair, Satish K., van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136673/
https://www.ncbi.nlm.nih.gov/pubmed/24866416
http://dx.doi.org/10.1021/cb5002526