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Oxetanyl Peptides: Novel Peptidomimetic Modules for Medicinal Chemistry
[Image: see text] The synthesis of novel oxetanyl peptides, where the amide bond is replaced by a non-hydrolyzable oxetanylamine fragment, is reported. This new class of pseudo-dipeptides with the same H-bond donor/acceptor pattern found in proteins expands the repertoire of peptidomimetics.
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136677/ https://www.ncbi.nlm.nih.gov/pubmed/25068485 http://dx.doi.org/10.1021/ol501590n |