Oxetanyl Peptides: Novel Peptidomimetic Modules for Medicinal Chemistry

[Image: see text] The synthesis of novel oxetanyl peptides, where the amide bond is replaced by a non-hydrolyzable oxetanylamine fragment, is reported. This new class of pseudo-dipeptides with the same H-bond donor/acceptor pattern found in proteins expands the repertoire of peptidomimetics.

Detalles Bibliográficos
Autores principales: McLaughlin, Martin, Yazaki, Ryo, Fessard, Thomas C., Carreira, Erick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136677/
https://www.ncbi.nlm.nih.gov/pubmed/25068485
http://dx.doi.org/10.1021/ol501590n

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