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Functional Probes of Drug–Receptor Interactions Implicated by Structural Studies: Cys-Loop Receptors Provide a Fertile Testing Ground: Miniperspective

[Image: see text] Structures of integral membrane receptors provide valuable models for drug–receptor interactions across many important classes of drug targets and have become much more widely available in recent years. However, it remains to be determined to what extent these images are relevant t...

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Detalles Bibliográficos
Autores principales: Van Arnam, Ethan B., Dougherty, Dennis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136689/
https://www.ncbi.nlm.nih.gov/pubmed/24568098
http://dx.doi.org/10.1021/jm500023m