Synthesis of Site-Specific DNA–Protein Conjugates and Their Effects on DNA Replication

[Image: see text] DNA–protein cross-links (DPCs) are bulky, helix-distorting DNA lesions that form in the genome upon exposure to common antitumor drugs, environmental/occupational toxins, ionizing radiation, and endogenous free-radical-generating systems. As a result of their considerable size and...

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Detalles Bibliográficos
Autores principales: Yeo, Jung Eun, Wickramaratne, Susith, Khatwani, Santoshkumar, Wang, Yen-Chih, Vervacke, Jeffrey, Distefano, Mark D., Tretyakova, Natalia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136702/
https://www.ncbi.nlm.nih.gov/pubmed/24918113
http://dx.doi.org/10.1021/cb5001795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136702/
https://www.ncbi.nlm.nih.gov/pubmed/24918113
http://dx.doi.org/10.1021/cb5001795

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