Cargando…

The Ca(2+) Sensor Protein Swiprosin-1/EFhd2 Is Present in Neurites and Involved in Kinesin-Mediated Transport in Neurons

Swiprosin-1/EFhd2 (EFhd2) is a cytoskeletal Ca(2+) sensor protein strongly expressed in the brain. It has been shown to interact with mutant tau, which can promote neurodegeneration, but nothing is known about the physiological function of EFhd2 in the nervous system. To elucidate this question, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Purohit, Pavitra, Perez-Branguli, Francesc, Prots, Iryna, Borger, Eva, Gunn-Moore, Frank, Welzel, Oliver, Loy, Kristina, Wenzel, Eva Maria, Grömer, Teja W., Brachs, Sebastian, Holzer, Max, Buslei, Rolf, Fritsch, Kristin, Regensburger, Martin, Böhm, Konrad J., Winner, Beate, Mielenz, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136728/
https://www.ncbi.nlm.nih.gov/pubmed/25133820
http://dx.doi.org/10.1371/journal.pone.0103976