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Tandem RNA Chimeras Contribute to Transcriptome Diversity in Human Population and Are Associated with Intronic Genetic Variants

Chimeric RNAs originating from two or more different genes are known to exist not only in cancer, but also in normal tissues, where they can play a role in human evolution. However, the exact mechanism of their formation is unknown. Here, we use RNA sequencing data from 462 healthy individuals repre...

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Detalles Bibliográficos
Autores principales: Greger, Liliana, Su, Jing, Rung, Johan, Ferreira, Pedro G., Lappalainen, Tuuli, Dermitzakis, Emmanouil T., Brazma, Alvis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136775/
https://www.ncbi.nlm.nih.gov/pubmed/25133550
http://dx.doi.org/10.1371/journal.pone.0104567