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Tandem RNA Chimeras Contribute to Transcriptome Diversity in Human Population and Are Associated with Intronic Genetic Variants
Chimeric RNAs originating from two or more different genes are known to exist not only in cancer, but also in normal tissues, where they can play a role in human evolution. However, the exact mechanism of their formation is unknown. Here, we use RNA sequencing data from 462 healthy individuals repre...
Autores principales: | Greger, Liliana, Su, Jing, Rung, Johan, Ferreira, Pedro G., Lappalainen, Tuuli, Dermitzakis, Emmanouil T., Brazma, Alvis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136775/ https://www.ncbi.nlm.nih.gov/pubmed/25133550 http://dx.doi.org/10.1371/journal.pone.0104567 |
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