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Cardiac Sympathetic Denervation in 6-OHDA-Treated Nonhuman Primates

Cardiac sympathetic neurodegeneration and dysautonomia affect patients with sporadic and familial Parkinson's disease (PD) and are currently proposed as prodromal signs of PD. We have recently developed a nonhuman primate model of cardiac dysautonomia by iv 6-hydroxydopamine (6-OHDA). Our in vi...

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Detalles Bibliográficos
Autores principales: Joers, Valerie, Dilley, Kristine, Rahman, Shahrose, Jones, Corinne, Shultz, Jeanette, Simmons, Heather, Emborg, Marina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136781/
https://www.ncbi.nlm.nih.gov/pubmed/25133405
http://dx.doi.org/10.1371/journal.pone.0104850