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Redox-Sensitive Induction of Src/PI3-kinase/Akt and MAPKs Pathways Activate eNOS in Response to EPA:DHA 6:1

AIMS: Omega-3 fatty acid products containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have vasoprotective effects, in part, by stimulating the endothelial formation of nitric oxide (NO). This study determined the role of the EPA:DHA ratio and amount, and characterized the mechanism...

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Detalles Bibliográficos
Autores principales: Zgheel, Faraj, Alhosin, Mahmoud, Rashid, Sherzad, Burban, Mélanie, Auger, Cyril, Schini-Kerth, Valérie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136823/
https://www.ncbi.nlm.nih.gov/pubmed/25133540
http://dx.doi.org/10.1371/journal.pone.0105102